| 发明名称 |
SPHINGOMYELIN SYNTHASE 2 (SMS2) DEFICIENCY ATTENUATES NFkB ACTIVATION, A POTENTIAL ANTI-ATHEROGENIC PROPERTY |
| 摘要 |
The present invention is directed to a method of screening for NFkappaB inhibiting agents, the method including the steps of administering a biologically effective amount of a candidate SMS2 inhibitor to at least one cell; and determining whether the candidate SMS2 inhibitor inhibits NFkappaB.
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| 申请公布号 |
US2009264514(A1) |
申请公布日期 |
2009.10.22 |
| 申请号 |
US20090426324 |
申请日期 |
2009.04.20 |
| 申请人 |
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK |
发明人 |
JIANG XIAN-CHENG;HALLEMARIAM TIRUNEH K. |
| 分类号 |
A61K31/7105;C12N9/99;C12Q1/02 |
主分类号 |
A61K31/7105 |
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