发明名称 |
Plasmodium falciparum antigens inducing protective antibodies |
摘要 |
<p>Proteins of peptides (I) which are recognised mainly by cytophilic antibodies (Ab) of subjects protected against Plasmodium infection and by non cytophilic Ab of subjects sensitive to infection are new. Pref (I) is 49kD merozoite surface protein of P falciparum, or a fragment of it, esp the sequence HisGluArgAlaLysAsnAlaTyrGlnLysAlaAsnGln AlaValLeuLysAlaLysGluAlaSerSerTyrAspTyr IleLeuGlyTrpGluPhe(Gly)3Val ProGluHisLysGluGluAsnMetLeuSerHisLeu TyrValSerSerLysAspLysGluAsnIleSerLysGlu AsnGlu (Ia).</p> |
申请公布号 |
EP1471150(A3) |
申请公布日期 |
2009.10.21 |
申请号 |
EP20040003945 |
申请日期 |
1993.10.18 |
申请人 |
INSTITUT PASTEUR |
发明人 |
DRUILHE, PIERRE;BOUHAROUN-TAYOUN, HASNAA;OEUVRAY, CLAUDE |
分类号 |
C12P21/08;A61K39/395;A61P33/06;C07K14/445;C12N1/21;C12N15/30;C12P21/04;G01N33/53 |
主分类号 |
C12P21/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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