发明名称 |
ANTI-TUMOR COMPOSITION COMPRISING TISSUE-ACCUMULATING CHITOSAN GEL |
摘要 |
<p>The present invention is achieved based on a novel finding that chitosan gel having retentivity in tissue has an antitumor activity and provides an antitumor composition containing chitosan gel having retentivity in tissue. The chitosan gel having retentivity in tissue of the present invention is preferably chitosan gel formed of a chitosan derivative having a carbohydrate chain introduced thereto as a base, to which a photoreactive group is further introduced to form crosslink with photo-irradiation; or chitosan gel formed of a polyion complex, which is formed of a carbohydrates chain-containing chitosan derivative and another substance, for example, an acidic polysaccharide. The antitumor composition of the present invention can suppress growth of a tumor without bringing it into contact with the tumor but by simply arranging it near the tumor.</p> |
申请公布号 |
EP2110131(A1) |
申请公布日期 |
2009.10.21 |
申请号 |
EP20080710333 |
申请日期 |
2008.02.07 |
申请人 |
YAIZU SUISANKAGAKU INDUSTRY CO., LTD.;NETECH INC. |
发明人 |
ISHIHARA, MASAYUKI;KANATANI, YASUHIRO;MATAHIRA, YOSHIHARU;YURA, HIROFUMI |
分类号 |
A61K31/722;A61K9/06;A61K31/726;A61K47/18;A61K47/26;A61P35/00;C08B37/08 |
主分类号 |
A61K31/722 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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