PROCESS FOR PREPARING DIBENZOTHIAZEPINE DERIVATIVES

摘要

A process for preparing a dibenzothiazepine derivat-ive such as dibenzo[b,f][1,4]thiazepin-11-one employable as a starting material for the preparation of 11-[4-(2- (2-hydroxyethoxy)ethyl)]-1-piperadinyldibenzothiazepine derivative which is known to be effective as an antipsy-chotic pharmaceutical, has the steps of reacting a nitro-benzene derivative with a thiosalicylic acid derivative, reducing the obtained 2-nitro-2'-carboxy-diphenylsulfide derivative, and subjecting the obtained 2-amino-2'- carboxy-diphenylsulfide derivative to dehydration-conden-sation reaction.