| 发明名称 |
CHIMERIC AND HUMANIZED ANTIBODIES TO alpha5beta1 INTEGRIN THAT MODULATE ANGIOGENESIS |
| 摘要 |
The present invention provides chimeric and humanized antibodies that specifically recognize alpha5beta1 integrin, and methods for using the antibodies for reducing or inhibiting angiogenesis in a tissue. Also provided are methods of determining therapeutically acceptable doses of the antibodies and pharmaceutical compositions including the same.
|
| 申请公布号 |
US2009259031(A1) |
申请公布日期 |
2009.10.15 |
| 申请号 |
US20070840854 |
申请日期 |
2007.08.17 |
| 申请人 |
RAMAKRISHNAN VANITHA;POWERS DAVID;JOHNSON DALE E;JEFFRY URSULA;BHASKAR VINAY |
发明人 |
RAMAKRISHNAN VANITHA;POWERS DAVID;JOHNSON DALE E.;JEFFRY URSULA;BHASKAR VINAY |
| 分类号 |
C07H21/00;C07K16/28 |
主分类号 |
C07H21/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
