发明名称 [1, 2, 4] TRIAZOLO [1, 5-A] PYRIMIDINE DERIVATIVES AS CHROMATOGRAPHIC ADSORBENT FOR THE SELECTIVE ADSORPTION OF IGG
摘要 The present invention relates to a chromatographic adsorbent for selectively adsorbing IgG, comprising the following formula and its corresponding enol-form, wherein X represents O, S, or NH; R1 represents H, C1-6 alkyl, C1-6 alkoxy, C1-6 alkoxy-C1-6 alkyl, Ar, -C(O)NHR3, -C(O)-R3 or halo; R2 represents H, C1-3 alkyl or halo; R3 represents H, C1-6 alkyl, C1-6 alkoxy, C1-6 alkoxy-C1-6 alkyl or Ar; n represents 0, 1, 2 or 3; Y represents a carrier. The present invention also relates to a method of producing said adsorbent as well as use thereof for separating substances by affinity chromatography.
申请公布号 US2009259029(A1) 申请公布日期 2009.10.15
申请号 US20090486155 申请日期 2009.06.17
申请人 GE HEALTHCARE BIO-SCIENCES AB 发明人 ALTERMAN MATHIAS;AXEN ANDREAS;CARREDANO ENRIQUE;GRONBERG ANNA;ZOU JINYU
分类号 C07K1/22 主分类号 C07K1/22
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