发明名称 Method for the Modulation of Function of Transcription Factors
摘要 There is provided a method of modulating the function of transcription factor by administering an effective amount of an oligonucleotide containing optimal nucleotide binding sites for the transcription factor. A therapeutic agent having an effective amount of an oligonucleotide for modulating function of transcription factors and a pharmaceutically acceptable carrier is also provided. Also provided is a treatment of patients having illnesses in which the activation of transcription factors play a role by administering to a patient an effective amount of an oligonucleotide which competitively binds the related transcription factor.
申请公布号 US2009258927(A1) 申请公布日期 2009.10.15
申请号 US20090391943 申请日期 2009.02.24
申请人 UNIVERSITY OF SOUTH FLORIDA 发明人 ZUCKERMAN KENNETH S.;LIU RICHARD Y.
分类号 A61K31/7088;A61K38/00;A61K48/00;C07H21/04;C12N15/113 主分类号 A61K31/7088
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