发明名称 |
Bis-arüülühend, seda sisaldav ravimpreparaat ning ühendi kasutamine kaaliumikanali blokaatorina toimiva ravimi valmistamiseks |
摘要 |
Ortho, ortho-substituted nitrogen-containing bisaryl compounds, processes for their preparation, their use as medicaments, and pharmaceutical preparations including their use as antiarrhythmic active compounds, for example, for the treatment and prophylaxis of atrial arrhythmias, e.g. atrial fibrillation (AF) or atrial flutters. Compounds of the invention include compounds of the formula I |
申请公布号 |
EE05220(B1) |
申请公布日期 |
2009.10.15 |
申请号 |
EE20030000225 |
申请日期 |
2001.11.24 |
申请人 |
AVENTIS PHARMA DEUTSCHLAND GMBH |
发明人 |
STEFAN PEUKERT;JOACHIM BRENDEL;HORST HEMMERLE;HEINZ-WERNER KLEEMANN |
分类号 |
A61K31/497;C07D239/28;A61K31/4418;A61K31/444;A61K31/505;A61K31/506;A61K45/00;A61P9/00;A61P9/06;A61P25/02;A61P43/00;C07D213/56;C07D213/81;C07D213/82;C07D241/24;C07D401/12;C07D401/14;C07D413/12;C07D413/14 |
主分类号 |
A61K31/497 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|