发明名称 |
FC-INTERFERON-BETA FUSIONSPROTEINE |
摘要 |
<p>Disclosed are Fc-interferon-beta (Fc-IFN-β) fusion proteins and nucleic acid molecules encoding them. The Fc-IFN-βfusion proteins include variants of the interferon-beta (IFN-β) protein that are altered to achieve enhanced biological activity, prolonged circulating half-life and greater solubility. Also disclosed are methods of producing the fusion proteins and methods of using the fusion proteins and/or nucleic acid molecules for treating diseases and conditions alleviated by the administration of interferon-beta.</p> |
申请公布号 |
AT443720(T) |
申请公布日期 |
2009.10.15 |
申请号 |
AT20050766761T |
申请日期 |
2005.06.28 |
申请人 |
MERCK PATENT GMBH |
发明人 |
GILLIES, STEPHEN;WATKINS, NIGEL;BAKER, MATTHEW;LO, KIN-MING |
分类号 |
C07K14/565 |
主分类号 |
C07K14/565 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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