| 发明名称 |
Phenyl-thiophene type vitamin D receptor modulators |
| 摘要 |
The present invention relates to novel, non-secosteroidal, phenyl-thiophene compounds with vitamin D receptor (VDR) modulating activity that are less hypercalcemic than 1alpha,25 dihydroxy vitamin D3. These compounds are useful for treating bone disease and psoriasis.
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| 申请公布号 |
US7601850(B2) |
申请公布日期 |
2009.10.13 |
| 申请号 |
US20030515403 |
申请日期 |
2003.05.22 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
DAHNKE KARL ROBERT;GAJEWSKI ROBERT PETER;JONES CHARLES DAVID;LINEBARGER JARED HARRIS;LU JIANLIANG;MA TIANWEI;NAGPAL SUNIL;SIMARD TODD PARKER;YEE YING KWONG;BUNEL EMILIO ENRIQUE;STITES RYAN EDWARD |
| 分类号 |
C07D333/06;C07D333/16;A61K31/381;A61K31/4025;A61K31/41;A61K31/505;A61P3/02;A61P3/10;A61P13/12;A61P17/02;A61P17/06;A61P17/10;A61P17/14;A61P19/00;A61P19/02;A61P19/10;A61P25/28;A61P29/00;A61P35/00;A61P43/00;C07D333/18;C07D333/20;C07D333/22;C07D333/24;C07D333/26;C07D333/34;C07D333/38;C07D333/40;C07D409/06;C07D409/12;C07D413/04;C07F9/6553 |
主分类号 |
C07D333/06 |
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