发明名称 |
PAPILLOMAVIRUS E2 POLYPEPTIDE USED FOR VACCINATION. |
摘要 |
<p>The present invention relates to the use of a nucleic acid molecule encoding at least one papillomavirus E2 polypeptide, or a vector, an infectious viral particle or a composition thereof for the preparation of a drug intended for treating a patient suffering from a persistent papillomavirus infection caused by at least one papillomavirus. The present invention also provides a vector comprising a nucleic acid molecule comprising a first nucleotide sequence encoding a papillomavirus E1 polypeptide and a second nucleotide sequence encoding a papillomavirus E2 polypeptide wherein the 3' portion of the first nucleotide which in the natural context is 100% identical to the 5' portion of the second nucleotide is modified so as to exhibit a percentage of identity between said portions of at most 75%.</p> |
申请公布号 |
MX2009008118(A) |
申请公布日期 |
2009.10.13 |
申请号 |
MX20090008118 |
申请日期 |
2008.01.29 |
申请人 |
TRANSGENE S.A. |
发明人 |
BALLOUL, JEAN-MARC;SILVESTRE, NATHALIE;BAUDIN, MARTINE |
分类号 |
C07K14/025 |
主分类号 |
C07K14/025 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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