发明名称 |
MODIFIED ACYL-ACP DESATURASE |
摘要 |
Disclosed is a method for modifying the chain length and double bond positional specificities of a soluble plant fatty acid desaturase. More specifically, the method involves modifying amino acid contact residues in the substrate binding channel of the soluble fatty acid desaturase which contact the fatty acid. Specifically disclosed is the modification of an acyl-ACP desaturase. Amino acid contact residues which lie within the substrate binding channel are identified, and subsequently replaced with different residues to effect the modification of activity.
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申请公布号 |
CA2263281(C) |
申请公布日期 |
2009.10.13 |
申请号 |
CA19972263281 |
申请日期 |
1997.08.01 |
申请人 |
BROOKHAVEN SCIENCE ASSOCIATES;KAROLINSKA INNOVATIONS AB |
发明人 |
CAHOON, EDGAR;SHANKLIN, JOHN;SCHNEIDER, GUNTHER;LINDQVIST, YLVA |
分类号 |
C12N9/02;C12N15/09;C12N1/15;C12N1/21;C12N5/10;C12N15/00;C12N15/11;C12N15/29;C12N15/53;C12N15/63;C12N15/82 |
主分类号 |
C12N9/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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