发明名称 |
DIAGNOSIS OF METAL ALLERGY THROUGH CYTOKINE RELEASE BY T-CELLS IN VITRO |
摘要 |
An in vitro method for diagnosing a contact allergy in a subject comprises: (i) providing (a) a contact allergen; (b) T-cells from said subject; and (c) a surface to which is immobilised a first specific binding agent capable of specifically binding to a cytokine released from a T-cell in response to sai d allergen; (ii) contacting said sample with said allergen under conditions which are suitable for (a) release of said cytokine by T cells that have bee n presensitised in vivo to said allergen; and (b) binding of said cytokine to said first specific binding agent; and (iii) detecting binding of said substance to said first specific binding agent. A kit which enables the meth od to be carried out is also described.
|
申请公布号 |
CA2440733(C) |
申请公布日期 |
2009.10.13 |
申请号 |
CA20022440733 |
申请日期 |
2002.03.12 |
申请人 |
MABTECH AB |
发明人 |
JAKOBSON, EVA |
分类号 |
G01N33/50;G01N33/53;G01N33/543;G01N33/68 |
主分类号 |
G01N33/50 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|