发明名称 STEREOSELECTIVE METHOD FOR PRODUCTION OF CLOPIDOGREL
摘要 FIELD: medicine. ^ SUBSTANCE: invention relates to the method for production of the compound of the formula (1a), being an inhibitor of thrombocyte aggregation (1a), where X is halogen atom. The method includes interaction of compounds of the formula (II), (II), where X has above mentioned value and Y and Z independently from each other are leaving groups, with optically active alkamine with formation of diastereoisomers admixture. ^ EFFECT: development of the new advantageous method for production of the bioactive compound. ^ 48 cl, 24 ex
申请公布号 RU2369610(C2) 申请公布日期 2009.10.10
申请号 RU20060137112 申请日期 2004.12.03
申请人 RATIOFARM GMBKH 发明人 STOKHEHNDL JURI;FRANTISHEK JAROSLAV;NESS VINFRID
分类号 C07C209/68;C07C211/08;C07C213/10;C07C215/08;C07C219/06;C07D333/20;C07D495/04 主分类号 C07C209/68
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