发明名称 HISTOGENETIC-FACTOR-INDUCED NERVE REGENERATION AND REPAIR
摘要 <P>PROBLEM TO BE SOLVED: To provide a therapeutic treatment method and a composition, for maintaining nerve pathways of mammalian cells. <P>SOLUTION: The method is for enhancing the survivability of neurons at risk of dyeing and comprises supplying a composition containing morphogen with a sufficient concentration for a sufficient time to neurons in order to reinforce survivability of neurons. The morphogen has one sequence selected from the group consisting of OP-1. OP-2, CBMP-2, Vgl(fx), Vgr(fx), DPP(fx), GDF(fx), and 60A(fx) and at least 70% amino acid sequence homology. <P>COPYRIGHT: (C)2010,JPO&INPIT
申请公布号 JP2009227679(A) 申请公布日期 2009.10.08
申请号 JP20090115655 申请日期 2009.05.12
申请人 STRYKER CORP 发明人 RUEGER DAVID C;KUBERASAMPATH THANGAVEL;OPPERMANN HERMANN;OZKAYNAK ENGIN;PANG ROY H L;COHEN CHARLES M
分类号 A61K38/00;G01N33/50;A61F2/00;A61K6/00;A61K38/18;A61K47/42;A61K48/00;A61L27/22;A61L27/24;A61P9/10;A61P25/00;A61P25/02;A61P25/14;A61P25/16;A61P25/28;A61P25/32;A61P31/04;A61P35/00;A61P37/06;A61P39/02;A61P43/00;C07K14/435;C07K14/47;C07K14/495;C07K14/51;C07K16/22;C12N5/10;C12N15/09;C12Q1/02;C12Q1/06;G01N33/53;G01N33/68 主分类号 A61K38/00
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