发明名称 |
FUSED THIOPHENE AND THIAZOLE DERIVATIVES AS PI3K KINASE INHIBITORS |
摘要 |
<p>A series of fused bicyclic thiophene and thiazole derivatives (I) which are substituted in the 2-position by an optionally substituted morpholin-4-yl moiety, and wherein the thiophene or thiazole ring is fused to a six-membered carbocyclic ring containing an alpha-hydroxyketone functionality, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.</p> |
申请公布号 |
WO2009122148(A1) |
申请公布日期 |
2009.10.08 |
申请号 |
WO2009GB00818 |
申请日期 |
2009.03.27 |
申请人 |
UCB PHARMA S.A.;PERRY, BENJAMIN GARFIELD;SABIN, VERITY MARGARET |
发明人 |
PERRY, BENJAMIN GARFIELD;SABIN, VERITY MARGARET |
分类号 |
A61K31/5377;A61K31/538;A61P9/00;A61P25/00;A61P27/02;A61P29/00;A61P35/00;A61P37/00;C07D277/82;C07D333/66;C07D417/04;C07D417/14 |
主分类号 |
A61K31/5377 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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