| 发明名称 |
Compositions and Methods for Producing a Composition |
| 摘要 |
The invention provides for mammalian cells capable of producing recombinant CTLA4-Ig and variants thereof. The invention also provides for compositions comprising CTLA4-Ig and formulations thereof. The invention further provides for methods for mass-producing CTLA4-Ig from mammalian cells capable of producing this recombinant protein, and for purifying the CTLA4-Ig. |
| 申请公布号 |
US2009252749(A1) |
申请公布日期 |
2009.10.08 |
| 申请号 |
US20060086786 |
申请日期 |
2006.12.19 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
LEISTER KIRK J.;SCHAEFER EUGENE J.;BATES RONALD CHARLES;BRAMHALL ELIZABETH A.;DIDIO DAVID MICHAEL;DONALDSON ROBERT;FLESHER ALAN R.;HAGGERTY HELEN GRAY;KIRKLEY DAVID HENRY;TABOR JOHN MALCOLM;TAY LEE K.;THAMMANA PALLAIAH;VELAYUDHAN AJOY;SMOLIN DAVID EDWARD;RUSSELL REB J.;VANDEN BOOM THOMAS JAMES;BROWNELL DEAN WOODROW;SCHRIMSHER JEFFREY;WHITEHEAD JOYCE PATRICIA |
| 分类号 |
A61K39/395;C07K1/14;C07K1/18;C07K16/18;C12P21/00 |
主分类号 |
A61K39/395 |
| 代理机构 |
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