| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide means for quantitatively analyzing a sugar chain contained in a biological sample by using a mass analytical method represented by MALDI-TOF MS. Ž<P>SOLUTION: A sugar chain analysis for analyzing a sample sugar chain, the sugar chain contained in the biological sample, by the mass analytical method includes the steps of: mixing a standard sugar chain, which is a predetermined amount of a known sugar chain, with the sample sugar chain; implementing mass spectrometry measurement of the mixture to obtain a mass spectrum; and comparing a signal strength of the sample sugar chain and that of the standard sugar chain to evaluate an amount of the sample sugar chain. In the sugar chain analysis, preferably, after a predetermined amount of the standard sugar chain is added to an unpurified sample containing the sample sugar chain, this is purified by sugar chain purification means to prepare a mixture of the sample chain sugar and the standard sugar chain, and then mass spectrometry measurement of the mixture is performed. Ž<P>COPYRIGHT: (C)2010,JPO&INPIT Ž
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