摘要 |
<P>PROBLEM TO BE SOLVED: To provide a surface modification method capable of uniformly introducing a phosphorylcholine analogous group into a gold substrate. Ž<P>SOLUTION: The surface modification method comprises the steps of: forming a self-assembled monolayer of a thiol having a reactive functional group via a gold-thiol bond on the surface of the gold substrate; allowing a surface modifier having a functional group represented by the general formula to bond with the self-assembled monolayer linked to the surface of the gold substrate by reacting the surface modifier with the self-assembled monolayer linked to the surface of the gold substrate. In the formula, R1, R2, and R3 individually represent a 1-6C alkyl group; m represents an integer of 2 to 6; and n is 1 or 2. Ž<P>COPYRIGHT: (C)2010,JPO&INPIT Ž
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