Use of tools, mapping systems, catheters, electrodes or any devices targeting any autonomic nerve(s) structure(s) in the human heart for the diagnostic, treatment and/or prevention of the recurrence of cardiac arrhythmias.

摘要

Treatment of atrial fibrillation, targeting the triggering autonomic nerve structures have been shown high efficacy for converting to a sinus rhythm state. However, the efficacy is limited to a short time (<3 months) with a high degree of recurrence of atrial arrhythmias. The recurrence rate was directly correlated to the time of follow-up which would support the role of the autonomic nerve regenerative (or re-establishment) activities for the incidence of the recurrence of atrial arrhythmias (ex. persistent atrial fibrillation). Furthermore, the recurrence degree of atrial fibrillation has not been shown any statistically significant difference between any of the currently used methods within any targeted area. Therefore, the long term inefficacy matter could be related either to the existing technologies or to their uses. The autonomic nerve' rotors which had triggered first the occurrence of atrial fibrillation would be regenerated its primary activities over time and therefore, triggering again their recurrence.