COMPOSITIONS AND METHODS FOR NUCLEIC ACID SEQUENCING
摘要
Compositions and methods for nucleic acid sequencing include template constructs that comprise double stranded portions in a partially or completely contiguous constructs, to provide for redundant sequence determination through one or both of sequencing sense and antisense strands, and iteratively sequencing the entire construct multiple times. Additional sequence components are also optionally included within such template constructs. Methods are also provided for the use and preparation of these constructs as well as sequencing compositions for their application.
申请公布号
WO2009120372(A2)
申请公布日期
2009.10.01
申请号
WO2009US01926
申请日期
2009.03.27
申请人
PACIFIC BIOSCIENCES OF CALIFORNIA, INC.;TRAVERS, KEVIN;OTTO, GEOFF;TURNER, STEPHEN;HEINER, CHERYL;MA, CONGCONG