发明名称 Small interfering RNAS as non-specific drugs
摘要 The present invention is directed to a method of modulating (e.g., inducing, inhibiting) activation of a double stranded RNA (dsRNA) signaling pathway, such as the dsRNA signaling pathway that accompanies RNA interference (RNAi) of a target RNA sequence, in a cell, comprising introducing into the cell small interfering RNA (siRNA) that degrades the target RNA sequence, and maintaining the cell under conditions in which RNAi of the target RNA sequence occurs and activation of the dsRNA signaling pathway is modulated in the cell.
申请公布号 US2009246833(A1) 申请公布日期 2009.10.01
申请号 US20080079594 申请日期 2008.03.27
申请人 THE CLEVELAND CLINIC FOUNDATION 发明人 MARQUES JOAO TRINDADE;WILLIAMS BRYAN R. G.
分类号 C12P19/34;C12N5/00;C12N15/11 主分类号 C12P19/34
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