发明名称 METHOD AND SUBSTANCE FOR DETECTING SEPSIS AND SEPSIS-LIKE SYSTEMATIC INFECTION
摘要 <P>PROBLEM TO BE SOLVED: To resolve a problem in a conventional diagnostic assay method wherein it was temporarily and generally considered that procalcitonin formed in the case of sepsis is the same as a calcitonin precursor, and in consequence, it is a peptide (procalcitonin 1-116) having a procalcitonin array of known 116 amino acid since a difference between know procalcitonin as a calcitonin precursor and procalcitonin formed in the case of sepsis was not explained. Ž<P>SOLUTION: Recombinant procalcitonin 3-116 is used in diagnosis and therapy of a sepsis disease, measurement of prohormones other than procalcitonin and dipeptidyl peptidase IV, and as a biomarker in diagnosis of sepsis. Ž<P>COPYRIGHT: (C)2010,JPO&INPIT Ž
申请公布号 JP2009222724(A) 申请公布日期 2009.10.01
申请号 JP20090152843 申请日期 2009.06.26
申请人 BRAHMS AG 发明人 BERGMANN ANDREAS;STRUCK JOACHIM;WEGLOEHNER WOLFGANG
分类号 G01N33/53;G01N33/68;A61P29/00;C07K14/585;C12N15/09;C12N15/16;C12P21/02;C12Q1/37;C12R1/19;G01N33/74 主分类号 G01N33/53
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