G COUPLED PROTEIN RECEPTORS ASSOCIATED WITH MYELOGENOUS HAEMATOLOGICAL PROLIFERATIVE DISORDERS AND USES THEREOF

摘要

The disclosure relates to methods and compositions effective in the diagnosis, prognosis and treatment of human hematopoietic cancers. In particular, the disclosure provides tumor- associated genes that encode G protein coupled receptors that are differentially expressed in hematopoietic tumor cells of myeloid origin compared with normal stem cells.