发明名称 3- (BENZO [D] [1,3] DIOXOL-5-YLMETHYL) -4- (THIO) OXO-2- (THIO) OXO-AZOLIDIN-5-YLIDENE DERIVATIVES AS ANTIBACTERIAL AGENTS
摘要 The present invention concerns novel azolidine compounds of Formula (I) wherein X denotes S, NH, CH2 or O, Y and W denotes each independently S or O, Q denotes CH or N, n and m are an integer from 0 to 2, and R1 and R2 denote independently from each other hydrogen, optionally substituted aryl, optionally substituted heterocyclyl, or an optionally substituted (C1-10) aliphatic group, R3 denotes hydrogen, lower alkyl, halogen, lower alkoxy, nitro, and R4 and R5 denote independently from each other hydrogen, halogen or alkyl, with the proviso that if one of R1 and R2 is hydrogen then the respective other one of R1 and R2 does not denote substituted or unsubstituted 2-furyland their salts, that are useful as pharmaceutical agents, e.g. as antibacterial agents, and to pharmaceutical compositions comprising such compounds.
申请公布号 US2009247516(A1) 申请公布日期 2009.10.01
申请号 US20070442970 申请日期 2007.10.08
申请人 KOTNIK MIHA;OBLAK MARKO;STEFANIC ANDERLUH PETRA;PREZELJ ANDREJ;HUMLJAN JAN;PLANTAN IVAN;URLEB UROS;SOLMAJER TOMAZ 发明人 KOTNIK MIHA;OBLAK MARKO;STEFANIC ANDERLUH PETRA;PREZELJ ANDREJ;HUMLJAN JAN;PLANTAN IVAN;URLEB UROS;SOLMAJER TOMAZ
分类号 A61K31/5377;A61K31/4439;A61K31/519;A61P31/04;C07D417/14;C07D471/04 主分类号 A61K31/5377
代理机构 代理人
主权项
地址