| 摘要 |
The present invention provides therapeutic compositions, kits and methods for treating nervous system injury in a mammal. Certain methods include administering to a mammal in need of such therapy an effective amount of angiopoietin-1 (Ang-1), or a functional analog thereof. Certain methods include administering a peptide having 4 to 20 amino acids that comprises an YVRL (SEQ ID NO:1) motif that may have activity at the alphavbeta3 or alpha5beta1 integrin receptor, such as C-16, or a compound that is an agonist at the alphavbeta3 and/or alpha5beta1 integrin receptor, which administration may be in combination with administration of Ang-1, or a functional analog thereof. |
