摘要 |
Provided herein is a highly pure paliperidone or a pharmaceutically acceptable salt thereof substantially free of keto impurity, 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-y1)-1- piperidinyl]ethyl]-2-methyl-7,8-dihydro-6H-pyrido[1,2-a]pyrimidin-4,9-dione, a process for the preparation thereof, and pharmaceutical compositions comprising highly pure paliperidone or a pharmaceutically acceptable salt thereof substantially free of keto impurity. |
申请人 |
ACTAVIS GROUP PTC EHF;BAPAT, UDAY, RAJARAM;JAYAMANI, MUNUSAMY;RAVISARAVANAN, SIVAJI;SODHA, VISHAL, AMRUTLAL;VALGEIRSSON, JON |
发明人 |
BAPAT, UDAY, RAJARAM;JAYAMANI, MUNUSAMY;RAVISARAVANAN, SIVAJI;SODHA, VISHAL, AMRUTLAL;VALGEIRSSON, JON |