发明名称 |
CORIN FOR TREATING OBESITY AND DIABETES |
摘要 |
<p>Provided herein are methods of inhibiting agouti or agouti-related protein (AGRP) in a cell or in an individual in need thereof, comprising administering to the cell or the individual an effective amount of an agent that induces corin expression, activity or a combination thereof in the cell or individual. The invention also provides a method of treating obesity in an individual in need thereof comprising administering to the individual an effective amount of an agent that enhances corin expression, activity or a combination thereof in the individual. Further provided is a method of treating diabetes type II in an individual in need thereof comprising administering to the individual an effective amount of an agent that enhances corin expression, activity or a combination thereof in the individual.</p> |
申请公布号 |
WO2009120760(A1) |
申请公布日期 |
2009.10.01 |
申请号 |
WO2009US38216 |
申请日期 |
2009.03.25 |
申请人 |
THE CLEVELAND CLINIC FOUNDATION;WU, QINGYU;JIANG, JINGJING;WANG, WEI |
发明人 |
WU, QINGYU;JIANG, JINGJING;WANG, WEI |
分类号 |
A61K38/48;A61P3/04;A61P3/10 |
主分类号 |
A61K38/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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