发明名称 Method for preparing 4-halogenated quinoline intermediates
摘要 This invention is directed to methods of preparing compounds of formula (I): comprising the step of reacting a compound of formula (II): with a reagent of formula POX<SUB>3 </SUB>and silica gel at a temperature greater than about 75° C., and wherein substitutions at X, PG, A, G, R<SUB>1 </SUB>and R<SUB>4 </SUB>are set forth in the specification.
申请公布号 ZA200809964(B) 申请公布日期 2009.09.30
申请号 ZA20080009964 申请日期 2008.11.24
申请人 WYETH 发明人 BERNIER, CAROLINE;SHAW, CHIA-CHENG
分类号 C07D 主分类号 C07D
代理机构 代理人
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