发明名称 |
USE OF I) A POLYGLYCOL AND II) AN ACTIVE DRUG SUBSTANCE FOR THE PREPARATION OF A PHARMACEUTICAL COMPOSITION FOR I) MITIGATING THE RISK OF ALCOHOL INDUCED DOSE DUMPING AND/OR II) REDUCING THE RISK OF DRUG ABUSE |
摘要 |
Abuse resistant polyglycol-based pharmaceutical compositions are disclosed. The composition contains one or more polyglycols and one or more active substances and it is resistant to crushing, melting and/or extraction. Moreover, such compositions have the same or lower solubility in ethanolic-aqueous medium, i.e. they are not subject to ethanol-induced dose dumping effect. |
申请公布号 |
EP2104493(A2) |
申请公布日期 |
2009.09.30 |
申请号 |
EP20080700888 |
申请日期 |
2008.01.16 |
申请人 |
EGALET A/S |
发明人 |
DOWNIE, Ken;PEDERSEN, Anders Vagnø;HAAHR, Anne-Mette;HEMMINGSEN, Pernille Høyrup;BAR-SHALOM, Daniel |
分类号 |
A61K9/22;A61K31/485 |
主分类号 |
A61K9/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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