Pharmaceutical composition having radiosensitive properties and comprising farnesyl-protein transferase inhibitor

摘要

The present invention relates to the use of a farnesyl-protein transferase inhibitor for the preparation of a pharmaceutical composition having radiosensitive properties and being intended for treating a tumor by in vivo administration before, during or after irradiation of the tumor, wherein the inhibitor of farnesyl-protein transferase is a compound of the general formula I, or a compound of the general formula II or III, which is metabolized in vivo to a compound of the general formula I, wherein the dotted line represents an optional bond; X represents oxygen or sulfur and other symbols have the meaning stated in the claims.