A novel use of bivalirudin in the treatment of acute coronary syndrome

摘要

A method of treating acute coronary syndrome (ACS) in a patient, comprising administering a therapeutically effective amount of an indirect thrombin inhibitor (unfractionated heparin UFH or low molecular weight heparin LMWH such as enoxaparin) to the patient, and subsequently administering a therapeutically effective amount of a direct thrombin inhibitor, namely bivalirudin, to the patient wherein the direct thrombin inhibitor is administered prior to and during a surgical procedure.