发明名称 |
Polyketides and their synthesis |
摘要 |
Biosyntheses of compounds whereof at least portions are polyketides produced by means of polyketide synthase (PKS) enzyme complexes are carried out after specific alterations have been made within the acyltransferase (AT) domains of the PKSs. Particular motifs in or near the substrate binding pocket are disclosed, such that alterations therein affect substrate specificity.
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申请公布号 |
US7595175(B2) |
申请公布日期 |
2009.09.29 |
申请号 |
US20030344738 |
申请日期 |
2003.07.31 |
申请人 |
BIOTICA TECHNOLOGY LIMITED |
发明人 |
PETKOVIC HRVOJE;KENDREW STEVEN GARY;LEADLAY PETER FRANCIS |
分类号 |
C12N15/09;C12P19/60;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/00;C12N9/10;C12N15/52;C12P19/62 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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