发明名称 AGENT FOR PREVENTING AND CURING HINDRANCE OF ISCHEMIC REPERFUSION
摘要 An agent for preventing and curing the hindrance of ischemic reperfusiton is disclosed which has as an active component thereof a chromanol glycoside represented by the following general formula: (see formula 1) [wherein R1, R2, R3, and R4 independently denote a hydrogen atom or a lower alkyl group, R5 denotes a hydrogen atom, a lower alkyl group, or a lower acyl group, X denotes a monosaccharide residue or an oligosaccharide residue which may have a lower alkyl group or a lower acyl group substituted for the hydrogen atom of the hydroxyl group of the saccharide residue, n denotes an integer of 0 - 6, and m denotes an integer of 1 - 6]. The agent, even in a small dosage, acts safely and effectively on the affected part and allows the hindrances of ischemic reperfusion induced in heart, stomach, small intestine, liver, spleen, kidney, brain, and skin, and the hindrance induced during the transplantation of an internal organ to be prevented and cured.
申请公布号 CA2319798(C) 申请公布日期 2009.09.29
申请号 CA19992319798 申请日期 1999.01.05
申请人 CCI CORPORATION;YOSHIKAWA, TOSHIKAZU 发明人 MURASE, HIRONOBU;YOSHIDA, NORIMASA;YOSHIKAWA, TOSHIKAZU
分类号 A61K31/7048;A61K31/70;A61K31/704;C07H15/26;C07H17/065 主分类号 A61K31/7048
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