NOVEL STABLE CRYSTALS OF SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVE AND PROCESS FOR PRODUCING THE SAME

摘要

Preparation of (S)-2-[[3-[N-[4-[(4-fluorophenoxy)phenyl] methyl]carbamoyl]-4-methoxyphenyl]methyl]butanoic acid (referred to as compound (I)) on an industrial scale lies in the finding of homogeneous crystals with excellent stability and the establishment of a preparative process thereof. Novel crystals of compound (I) homogeneous and excellent in the stability characterized by exhibiting the diffraction angles (2.theta.) at least 17.7.degree., 19.0.degree. and 24.1.degree. in the X-ray powder diffraction are provided by recrystallizing from an alcoholic solvent.