DRUG COMPOSITION OF POLYMER MICELLE AND PREPARATION METHOD THEREOF

摘要

PURPOSE: A polymer micelle drug composition is provided to effectively solubilize pioglitazone, rosiglitazone and troglitazone which are insoluble drugs. CONSTITUTION: A polymer micelle drug composition comprises amphiphilic diblock copolymer and one kind of insoluble drug. The amphiphilic diblock copolymer comprises hydrophilic block and one kind of hydrophobic block. The hydrophilic block contains polyakylene glycol. The hydrophobic block is selected among a group of polylactide, polyglycolide and their copolymer. The insoluble drug is selected among a group of pioglitazone, rosiglitazone, troglitazone and their mixture.