发明名称 Alpha-crystalline form of substituted selenoxanthenes and the method of its preparation
摘要 The invention pertains to field of organic chemistry, medicine, pharmacology, foods and cosmetics industry, particularly, to manufacturing technology of selenoxanthenes; the invention may be used in manufacturing of food supplements, pharmaceutical and cosmetic products, having bioactive properties, of a wide spectrum of activity. The proposed compound is the alpha-crystalline form of 9-phenyl-symmetrical-octahydroselenoxanthene with exhibits antioxidant, detoxifying, immunomodulating, anti-atherogenic, anti-sclerotic, anabolic and hypolipidemic properties, and has the following structural formula: Its powder X-ray diffractogram (obtained from a Cu-K X-ray source) has characteristic diffractions in degrees of the diffraction angle 2theta as 6.0, 12.0, 15.0, 17.0, 19.0, 20.0, 21.5, 21.7, 20.9, 25.0, 27.0, 28.0, 29.0, 37.0; the melting point of 96.8° C. The crystalline form of the respective 9-R-symmetrical-selenoxantene product is obtained by crystallization from a weakly polar or a non-polar solvent.
申请公布号 US2009240048(A1) 申请公布日期 2009.09.24
申请号 US20090406461 申请日期 2009.03.18
申请人 MEDBIOPHARM LTD 发明人 ROZIEV RAKHIMDZHAN A.;TSYB ANATOLY F.;GONCHAROVA ANNA YA.;KHOMICHONOK VIKTOR V.;PODGORODNICHENKO VLADIMIR K.
分类号 C07D345/00 主分类号 C07D345/00
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