SPECIFIC MARKERS FOR METABOLIC SYNDROME

摘要

PROBLEM TO BE SOLVED: To provide a comparatively simple and high cost efficiency technique for measuring, monitoring and following up the levels of visceral adipose tissue. SOLUTION: This invention provides polypeptides which are predominately expressed in visceral adipose tissue which can be used as markers for the measurement of the levels of visceral adipose tissue in a subject. The invention also provides methods for the measurement of the levels of visceral adipose tissue by obtaining a biological sample and detecting and/or measuring the increase of one or more polypeptides as disclosed herein. Screening methods relating to agonists and antagonists of the specific polypeptides disclosed herein are provided. Antibodies may also be raised against these polypeptide markers for the detection and/or treatment of metabolic syndrome related comorbidities. COPYRIGHT: (C)2009,JPO&INPIT