发明名称 6-SUBSTITUTED INDOLE-3-CARBOXYLIC ACID AMIDE COMPOUNDS HAVING SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR ANTAGONIST BIOLOGICAL ACTIVITY
摘要 The invention provides compounds represented by the formula I, each of which compounds may have sphingosine-1-phosphate receptor agonist and or antagonist biological activity: Formula (I) and wherein the variables Y, R4, n, o, A, A1, A2, X, Z, R1, R3, R2, p, q and r are as defined in the specification. These compounds are useful for treating a disease or condition selected from the group consisting of glaucoma, dry eye, angiogenesis, cardiovascular conditions and diseases, and wound healing.
申请公布号 KR20090101307(A) 申请公布日期 2009.09.24
申请号 KR20097016762 申请日期 2008.01.10
申请人 ALLERGAN, INC. 发明人 BEARD RICHARD L.;YUAN HAIQING
分类号 C07D405/14;A61K31/404;A61P27/00;C07D401/06 主分类号 C07D405/14
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