COMPOSITION COMPRISING PPARgamma PHOSPHORYLATION MUTANT FOR THE PREVENTION OR TREATMENT OF ATHEROSCLEROSIS AND RESTENOSIS

摘要

PURPOSE: A composition for preventing or treating atherosclerosis and restenosis, which contains PPARγ phosphorylation mutant is provided to prevent the symptom of restenosis. CONSTITUTION: A composition for preventing or treating atherosclerosis and restenosis comprises a mutant which suppresses phosphorylation at 112th serine of PPARγ amino acid sequence or mutation-inducing material. The mutant is a mutant which 112th serine is substituted with other amino acid residue in the PPARγ amino acid sequence.