发明名称 |
POLYPEPTIDE HAVING GLYOXYLASE III ACTIVITY, POLYNUCLEOTIDE ENCODING THE SAME AND USES THEREOF |
摘要 |
The present invention relates to a novel polypeptide having the enzymatic activity of conversion of methylglyoxal to lactic acid in a single step (known as glyoxalase III activity), a polynucleotide having a nucleotide sequence encoding such polypeptide and uses thereof. Theinvention relates to the modulation of the glyoxalase III activityin a microorganism by varying the expression level of the polynucleotide coding for such polypeptide.The invention also relates to the production of commodity chemicals, especially 1,2-propanediol, acetol, and lactic acid by fermenting microorganisms wherein their glyoxalase III activity is modulated. |
申请公布号 |
WO2009115114(A1) |
申请公布日期 |
2009.09.24 |
申请号 |
WO2008EP53224 |
申请日期 |
2008.03.18 |
申请人 |
METABOLIC EXPLORER;VOELKER, FRANCOIS;SOUCAILLE, PHILIPPE |
发明人 |
VOELKER, FRANCOIS;SOUCAILLE, PHILIPPE |
分类号 |
C12N15/01;C12N9/02;C12P7/18;C12P7/28 |
主分类号 |
C12N15/01 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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