| 摘要 |
Systems and methods are provided for determining the pressure-volume relationship for one or more chambers of a heart. An implantable device includes a catheter including a distal end sized for introduction into a chamber of a heart, a pressure sensor for measuring pressure within the chamber, and a resistance sensor for measuring fluid resistance within the chamber. A processor coupled to the catheter obtains pressure data from the pressure sensor and fluid resistance data from the resistance sensor. The processor approximates fluid volume within the chamber as a function of time and determines one or more pressure-volume loops based upon the pressure data and the fluid volume. In one embodiment, the catheter is a lead including a pacing electrode and a controller including the processor delivers pulses to the pacing electrode based upon the pressure-volume loops to deliver electrical therapy to the heart.
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