发明名称 |
FLUOROGENIC PEPTIDES AND THEIR METHOD OF PRODUCTION |
摘要 |
<p>A method of making a fluorogenic peptide with an acridone fluorophor is provided, the method comprising the steps of: (a) providing an acridone derivative, said acridone derivative having first and second reactive groups (or precursors thereof), (b) providing a solid phase support provided with reactive species for reacting with the first reactive group of the acridone derivative (c) causing the solid phase support and acridone derivative to react so that the acridone derivative is attached to the solid phase support (d) providing the peptide or reagents for the formation of the peptide, and (e) subsequent to step (c), causing the reaction of the second acridone reactive group with the peptide or one or more of the reagents for the formation of the peptide.</p> |
申请公布号 |
WO2009112791(A1) |
申请公布日期 |
2009.09.17 |
申请号 |
WO2008GB00930 |
申请日期 |
2008.03.14 |
申请人 |
ASSAYMETRICS LIMITED;GRAVES, PIERRE;SMITH, JOHN, ANTHONY |
发明人 |
GRAVES, PIERRE;SMITH, JOHN, ANTHONY |
分类号 |
C07K1/04;C07K1/06;C07K1/13;C12Q1/37;G01N33/52 |
主分类号 |
C07K1/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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