RATIONALLY-DESIGNED MEGANUCLEASES FOR MAIZE GENOME ENGINEERING

摘要

The invention relates to the field of molecular biology and recombinant nucleic acid technology. In particular, the invention relates to a rationally-designed, non-naturally- occurring meganuclease with altered DNA recognition sequence specificity which recognizes and cleaves a unique DNA site in the maize genome. The invention also relates to methods of producing engineered maize plants using such meganuc leases.