IMMUNO-BASED BOTULINUM TOXIN SEROTYPE A ACTIVITY ASSAYS
摘要
<p>The present specification discloses SNAP-25 compositions, methods of making a-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, a-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, methods of detecting BoNT/A activity, and methods of detecting neutralizing a-BoNT/A antibodies.</p>
申请公布号
WO2009114748(A1)
申请公布日期
2009.09.17
申请号
WO2009US37046
申请日期
2009.03.13
申请人
ALLERGAN, INC.;FERNANDEZ-SALAS, ESTER;WANG, JOANNE;GARAY, PATTON, E.;WONG, LINA, S.;HODGES, D., DIANNE;AOKI, KEI, ROGER
发明人
FERNANDEZ-SALAS, ESTER;WANG, JOANNE;GARAY, PATTON, E.;WONG, LINA, S.;HODGES, D., DIANNE;AOKI, KEI, ROGER