发明名称 |
GENERATION OF BIOLOGICAL PACEMAKER ACTIVITY |
摘要 |
Compositions and methods for enhancing hyperpolarization-activated cation inward current and disrupting inwardly rectifying potassium current of cells are described. The compositions and methods may be employed to cause the cells to become biological pacemaker cells, e.g. to become more like SA node cells, and to undergo spontaneous oscillating action potentials.
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申请公布号 |
US2009233990(A1) |
申请公布日期 |
2009.09.17 |
申请号 |
US20080263281 |
申请日期 |
2008.10.31 |
申请人 |
CHO HEE CHEOL;MARBAN EDUARDO;SIGG DANIEL |
发明人 |
CHO HEE CHEOL;MARBAN EDUARDO;SIGG DANIEL |
分类号 |
A61K31/7052;A61P9/00;C12N5/00;C12N15/63;C12N15/85;C12N15/86 |
主分类号 |
A61K31/7052 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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