PATCH

摘要

Provided is a patch which has a high storage stability and transdermal absorbability of midodrine or a pharmacologically acceptable salt thereof and exhibits an excellent stickiness. A patch which contains in the ointment layer midodrine or a pharmacologically acceptable salt thereof and a specific acrylic pressure-sensitive adhesive together with one or both of a saturated aliphatic monohydric alcohol (A) and a saturated fatty acid ester each in a definite amount. Owing to this constitution, the solubility and diffusibility of the midodrine or a salt thereof in the ointment layer are improved and thus the transdermal absorbability is elevated without damaging the storage stability of the midodrine or a salt thereof. Thus, a sufficient amount of the midodrine or a salt thereof is contained in the diffused state in the ointment layer, which enables continuous administration of midodrine.