发明名称 |
Diagnostic and Therapeutic Potential of Immune Globulin Intravenous (IGIV) Products |
摘要 |
The present invention provides IGIV and IGIV enriched for binding to amyloid fibrils and to partially denatured amyloidogenic precursor polypeptides. The present invention also provides methods for obtaining IGIV enriched for binding to amyloid fibrils and to partially denatured amyloidogenic precursor polypeptides. The IGIV recognizes amyloid fibrils and partially denatured amyloidogenic precursor polypeptides. They are useful for treating diseases and conditions associated with amyloid deposition. The IGIV of the present invention also are useful for diagnosing and detecting amyloid deposition.
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申请公布号 |
US2009232733(A1) |
申请公布日期 |
2009.09.17 |
申请号 |
US20060911506 |
申请日期 |
2006.04.13 |
申请人 |
O'NUALLAIN BRIAN;HRNCIC RUDI;WALL JONATHAN S;SOLOMON ALAN |
发明人 |
O'NUALLAIN BRIAN;HRNCIC RUDI;WALL JONATHAN S.;SOLOMON ALAN |
分类号 |
A61K51/00;A61B5/055;A61B8/00;A61K39/395;A61K49/00;C07K1/16 |
主分类号 |
A61K51/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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