发明名称 |
PTTG1 AS A BIOMARKER FOR CANCER TREATMENT |
摘要 |
The present invention relates to the use of pituitary tumor transforming gene 1 (PTTG1) as a biomarker for diagnosing cancer as well as for determining cancer treatment responsiveness. In one embodiment, the present invention provides a method of treating cancer by inhibiting the expression of PTTG1, and administering a therapeutically effective amount of Aurora kinase inhibitor, HDAC inhibitor and/or ROS-generating agent. |
申请公布号 |
WO2009114817(A2) |
申请公布日期 |
2009.09.17 |
申请号 |
WO2009US37178 |
申请日期 |
2009.03.13 |
申请人 |
CEDARS-SINAI MEDICAL CENTER;TONG, YUNGUANG;MELMED, SHLOMO |
发明人 |
TONG, YUNGUANG;MELMED, SHLOMO |
分类号 |
A61K48/00 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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