发明名称 |
PLASMA BIOMARKER FOR LIVER CANCER DIAGNOSIS COMPRISING LIVER CARBOXYLESTERASE 1 AND SCREENING METHOD FOR CANCER DIAGNOSIS |
摘要 |
A marker for diagnosing liver cancer of which expression is increased in plasma of patient is provided to detect a protein in plasma and early diagnose liver cancer by confirming the expression of protein. A composition of marker for diagnosing liver cancer comprises a liver-carboxyl esterase 1 protein in plasma as an active ingredient. The amount of the liver-carboxylesterase 1 protein of patient who suffers from liver cancer is more than that normal person in plasma. A method for screening liver cancer comprises: a first step of confirming the presence of the liver-carbxylesterase 1 from human blood sample using nano liquid chromatography and antibody immunoprecipitation; and a second step of detecting normal person and patient using immunoprecipitation, immnuoblotting, and nano liquid chromatography mass spectrometry.
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申请公布号 |
KR20090098366(A) |
申请公布日期 |
2009.09.17 |
申请号 |
KR20080023707 |
申请日期 |
2008.03.14 |
申请人 |
INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY |
发明人 |
PAIK, YOUNG KI;NA, KEUN |
分类号 |
C12Q1/44;G01N33/574;G01N33/576 |
主分类号 |
C12Q1/44 |
代理机构 |
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